Targeting BUB3 in combination with paclitaxel inhibits proliferation of glioblastoma cells by enhancing cellular senescence

Authors

  • Patrícia M. A. Silva UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal; TOXRUN - Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal.
  • Ana V. Nascimento UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal.
  • Olga Martinho Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.
  • Rui M. Reis Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.
  • Hassan Bousbaa UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal; Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n 4450-208 Matosinhos, Portugal.

DOI:

https://doi.org/10.51126/revsalus.v4iSup.267

Keywords:

glioblastoma, BUB3, paclitaxel, mitosis, senescence

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Published

2022-04-06

How to Cite

Targeting BUB3 in combination with paclitaxel inhibits proliferation of glioblastoma cells by enhancing cellular senescence. (2022). RevSALUS - International Scientific Journal of the Academic Network of Health Sciences of Lusophone, 4(Sup), 37. https://doi.org/10.51126/revsalus.v4iSup.267